Kałusz (currently Kalush, Ukraine) has very long brewing traditions, dating back to at least 1565. If the current brewery were historically connected with an enterprise listed in the lustration documents from Halicz (Halych; Ukr: Га́лич) and Przemyśl lands, it would be the oldest brewery in today’s Ukraine.

However, very little is known about the beginnings of the existing brewery. The only confirmed fact is that in 1870, the company was taken over by three Jewish industrialists from Kałusz: Mojżesz Weissmann, Aba Mühlstein, and Leib Spindel. In the 1890s, the company erected a malt plant which produced its own fermented grain. The plant also had a spirit refinery and a rum and liquor factory (the most popular brand was the 'Szpindlówka' vodka). Several types of beer were brewed: "Imperialne" (Imperial), "Marcowe" (March), "Exportowe" (Export), "Dubetowe" (Double), "Kaluszer Löwenbräu" and "Kaluszer Kronenbier." The last two were produced for the Bukovina market – the company had a representative office in Czerniowce (Chernivtsi; Ukr. Чернівці); it was headed by Dawid Frenkel, whose name was included on the labels. With the introduction of the steam engine, the company quickly developed and increased production. It employed ca. 200 people – residents of Kałusz and the nearby villages of Zagórze (Zahirya) and Podhorki. On the eve of World War I, the company brewed almost 40,000 hl of beer a year. The brewery operated until the outbreak of World War II.

The Kalush Memorial Book includes the account of Zusja Szpilman – daughter of one of the brewery's employees. She writes that during World War I, after her family house had burned down, they were given a replacement apartment in the brewery.

“Aba Mühlstein and Leib Spindel, the brewery owners – I remember them as vividly as if they were standing right in front of me. They both always wore black suits and held Tyrolean walking sticks in their hands. When they got old, their children became the managers: Zelig Mühlstein and his son Moshe as well as Shlomo, grandson of Leib. I remember very clearly the noise and bustle of the brewery. It was a large factory employing many workers, mainly Ukrainians. The beer was very tasty, praised all over Galicia. During my childhood the brewery was the only place in the city where a turbine (100 horsepower) produced electricity. That is why our house had electric lighting and hot water in the tap. All my friends would visit us to enjoy a warm bath.”

The permanent exhibition of the Historical Museum of Kalush District features original corks and beer labels from the brewery as well as an invoice from 1911 adorned with the image of the production plant. The brewery itself keeps a collection of original pre-war beer bottles and an oak barrel bearing inscriptions in Polish and production date: 1918.