With typical features for sacred buildings of the late Renaissance, the synagogue of Pińczów has a form of a fortification. A florin Santi Gucci, probably the architect of the building, designed a cube-shaped mass with a roof hidden behind a simple attic without any decorations. A thick wall with high windows is supported with massive supports located in corners .

The interior is entered through a spacious vestibule which was also used as a room of the meeting of both the community’s management and rabbi’s court. The room enraptures with its recently reconstructed rich polychrome of the ceiling. Among rich floral ornaments one can find Hebrew inscriptions; there are also animals, birds as well as stylized flowers and fruit. In keeping with tradition, the floor of the prayer hall is lowered, therefore, there are a few stairs leading there
Out of the former décor,  the late Renaissance aron ha-kodesz, flanked with two columns and toped with a triangular finial, have survived there .

Being 30 meters long, 25 meters wide, and 18 meters high, the prayer hall is an impressive room with a barrel vault. As for the women’s gallery, it is located in the southern part of the building and has a cross vault.

During the occupation in Pińczów, a ghetto was established for over 3,000 inhabitants. Some of them were executed by firing squad in a nearby forest whereas others were taken to the German nazi death camp in Treblinka.

During the Nazi occupation the synagogue was used as garages and for the following years it housed a warehouse of building materials and pesticides.

It was not until 1970s when a decision was made to change the building into the Museum of Ponidzie. The renovation of the building has been carried out for over 20 years. Consequently, the roof has been reconstructed and the building has been protected against damp. Moreover, conservatory works have been started to renovate polychromes and the Aron ha-kodesz as well as to read and reconstruct inscription found on walls of the prayer hall. However, the stony bimah located in the center of the hall has not been rebuilt yet; only a mark was made on the floor in the place where the bimah used to be situated by WWII.